Rabbit Anti-FGFR3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:FGFR3
IR:Immunogen Range:501-600/801
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2261
Swiss Prot:P22607
Source:KLH conjugated synthetic peptide derived from human FGFR3:501-600/801
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:1000-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Chicken
Dog
Cow
Horse
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用!
關(guān)鍵字: FGFR3;ACH;CD333;CD333 antigen;CEK2;FGFR 3;JTK4;FGFR3_HUMAN;
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