Rabbit Anti-Secretin receptor Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Secretin receptor
IR:Immunogen Range:188-280/440
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6344
Swiss Prot:P47872
Source:KLH conjugated synthetic peptide derived from human Secretin receptor:188-280/440
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The receptor for secretin is a class 2 (or class B) G protein coupled receptor that signals through Gs to stimulate cAMP production. Along with its traditional role in the pancreas, studies in secretin-deficient mice have shown miscommunication between the CA3 Schaffer collateral and CA1 pyramidal neurons, causing a deficiency in synaptic transmission. This miscommunication of CA1 dendrites is found in Autism, Rett Syndrome, and most forms of mental retardation, suggesting secretin could be a potential target for treatment of these disorders.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Rabbit
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： Secretin receptor;6530402O03Rik;MGC102218;MGC93381;SCTR;SR; SCT-R;SCTR_HUMAN;
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