Rabbit Anti-Titin Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Titin
IR:Immunogen Range:2601-2800/34350
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7273
Swiss Prot:Q8WZ42
Source:KLH conjugated synthetic peptide derived from human Titin/CMD1G:2601-2800/34350
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Titin, also known as connectin, is a large protein involved in the temporal and spatial control of the assembly of the highly ordered sarcomeres (contractile units) of striated muscle. In addition to sarcomere assembly Titin also functions to maintain the structural integrity of the contracting myofibrils within the muscle and to organize the machinery for condensation of chromosomes in dividing cells. Titin is a giant protein composed of 27,000 amino acids and contains an autoregulated serine kinase catalytic domain as well as a calcium/calmodulin binding region that are involved in its activation. Activated Titin phosphorylates the muscle protein telethonin, a sarcomeric protein abundant in heart and skeletal muscle, implicating Titin activity in the reorganization of the cytoskeleton during myofibrillogenesis.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/test)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Titin;TTN;MPRM;CMD1G;CMH9;CMPD4;DKFZp451N061;TITIN_HUMAN;
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