Rabbit Anti-Phospho-PFKFB3/PFK2 (Ser467) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-PFKFB3/PFK2 (Ser467)
IR:Immunogen Range:LA(p-S)PE
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5209
Swiss Prot:Q16875
Source:KLH conjugated synthesised phosphopeptide derived from human PFK2 around the phosphorylation site of Ser467:LA(p-S)PE
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Pig
Cow
Horse
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Phospho-PFKFB3/PFK2 ;6 phosphofructo 2 ki;6PF 2-K/Fru 2,6 P2as;iPFK 2;IPFK2;PFK/FBPase 3;uPFK 2;F263_HUMAN;
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