Rabbit Anti-phospho-P53 (Ser15) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-P53 (Ser15)
IR:Immunogen Range:PL(p-S)QE
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7157
Swiss Prot:P04637
Source:KLH conjugated Synthesised phosphopeptide derived from human P53 around the phosphorylation site of Ser15:PL(p-S)QE
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg /test)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Dog
Pig
Cow
Rabbit
Sheep
Guinea Pig
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： phospho-P53 (Ser15);p53 (Phospho-Ser15);P53 (phospho S15);p-P53 (Ser15);HGNC11998; Cys 51 Stop;TP53;P53_HUMAN;
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