Rabbit Anti-phospho-Tau (Ser404) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-Tau (Ser404)
IR:Immunogen Range:IG(p-S)TE
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4137
Swiss Prot:P10636
Source:KLH conjugated Synthesised phosphopeptide derived from human Tau around the phosphorylation site of Ser404:IG(p-S)TE
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： phospho-Tau (Ser404);Tau (phospho S404); p-Tau (phospho S404;Tau(Phospho-Ser404);MAPT Microtuble-ass;AI413597;AW045860;TAU_HUMAN;
上海滬震實業(yè)有限公司是一家集研發(fā)、生產和銷售于一體的生命科學實驗室產品生物科技企業(yè)。主營產品：試劑盒，ELISA試劑盒，抗體，重組蛋白，血清，胎牛血清，細胞，原代細胞 細胞培養(yǎng)試劑，常用生化試劑。