Rabbit Anti-LXR alpha Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:LXR alpha
IR:Immunogen Range:351-447/447
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:10062
Swiss Prot:Q13133
Source:KLH conjugated synthetic peptide derived from human LXR alpha:351-447/447
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： LXR alpha;Liver X receptor alp;LXRa;LXRA;NR1H3;RLD1;Oxysterols receptor ;NR1H3_HUMAN;
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