Rabbit Anti-KIF13B Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:KIF13B
IR:Immunogen Range:351-450/1826
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:23303
Swiss Prot:Q9NQT8
Source:KLH conjugated synthetic peptide derived from human KIF13B:351-450/1826
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:KIF13B is also known as Kinesin-like protein GAKIN or GAKIN and is a 1,826 amino acid protein that is widely expressed in tissues, with highest expression in brain and kidney. KIF13B is localized to the cytoplasm, as well as to the cytoskeleton, and is thought to be a microtubule-dependent motor protein which is able to bind to a variety of proteins in order to traffic them to various locations throughout the cell. KIF13B belongs to the kinesin-like protein family and possesses three domains typical of the kinesin-like protein family, namely an N-terminal motor domain with an ATP-binding motif, an FHA domain which is known to bind diverse cargos and a large stalk domain involved in protein-protein binding. Additionally, KIF13B has a microtubule-interacting sequence which is known as the CAP-Gly domain at its C-terminus. The CAP-Gly domain is highly conserved domain among eukaryotes, and in humans, defects in the CAP-Gly domain are implicated in many diseases affecting the trafficking of vesicles, neuromuscular junctions and lysosome proliferation.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:200-800)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用!
關(guān)鍵字: KIF13B;GAKIN;KIAA0639;KIF 13B;KIF13B;Kinesin 13B;OTTHUMP00000225649;KI13B_HUMAN;
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