Rabbit Anti-MKP1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:MKP1
IR:Immunogen Range:151-250/367
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1843
Swiss Prot:P28562
Source:KLH conjugated synthetic peptide derived from human DUSP1:151-250/367
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： MKP1;DUSP1;CL100;DUSP 1;CL100;PTPN 10;3ch134;Mkp1;
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