Rabbit Anti-Thyroid hormone receptor alpha Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Thyroid hormone receptor alpha
IR:Immunogen Range:81-180/490
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7067
Swiss Prot:P10827
Source:KLH conjugated synthetic peptide derived from human Thyroid hormone receptor alpha:81-180/490
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Thyroid hormone receptors (TR) are ligand dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences called hormone response elements following activation by the appropriate hormone. Thyroid hormones, through their interaction with TR, effect metabolic processes, growth and development in many tissues by regulating the expression of genes for growth hormone, malic enzyme and several hepatic proteins. There are two forms of TR; TR alpha (on chromosome 17) and TR beta (on chromosome 3). Each of these isoforms also has two isoforms; TR alpha 1 and TR alpha 2, and TR beta 1 and TR beta 2 respectively. TR alpha 1 and 2 are identical through amino acid 370, where their sequences diverge. TR alpha 2, which does not bind T3 and is a strong negative regulator of the functional TR, is 80 amino acids longer than TR alpha 1
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Pig
Horse
Rabbit
Sheep
Guinea Pig
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Thyroid hormone rece;AR7;c-erbA-1;C-erbA-alpha;CHNG6;EAR7;ERBA alpha;THA_HUMAN;
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