Rabbit Anti-MGLUR3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:MGLUR3
IR:Immunogen Range:365-460/879
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2913
Swiss Prot:Q14832
Source:KLH conjugated synthetic peptide derived from human Metabotropic Glutamate Receptor 3:365-460/879
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Flow-Cyt(5μg/Test)
Cross Reactive Species:Human
Mouse
Rat
Cow
Horse
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： MGLUR3;G protein coupled;GLUR3;GLUR 3;lutamate metabotropi;GPRC1C;GRM3;GRM3_HUMAN;
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