Rabbit Anti-CDK8 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CDK8
IR:Immunogen Range:251-350/464
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1024
Swiss Prot:P49336
Source:KLH conjugated synthetic peptide derived from human CDK8:251-350/464
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016][provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Horse
Rabbit
Cat
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： CDK8;Cyclin Dependent Kin; Cell Division Kinas;Cell division protei;K35;Mediator complex sub;Protein kinase K35;CDK8_HUMAN;
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