Rabbit Anti-MTLC Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:MTLC
IR:Immunogen Range:21-100/235
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:80177
Swiss Prot:Q8N699
Source:KLH conjugated synthetic peptide derived from human MTLC:21-100/235
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:MTLC is a 235 amino acid nuclear protein that is thought to regulate certain myc target genes. Downregulated in gastric cancer tissues, MTLC is expressed in the hepatocellular carcinoma cell line, Bel7402. Overexpression of MTLC is thought to influence tumorigenic conversion, promotion of apoptosis genomic instability and inhibition of hematopoietic differentiation. The gene encoding MTLC maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： MTLC;yc target 1;Myc target 1;YCT 1 protein;yc target in myeloid;FLJ21269;MGC156309;MYCT1_HUMAN;
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