Rabbit Anti-Cytochrome b245 Light Chain Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Cytochrome b245 Light Chain
IR:Immunogen Range:21-120/195
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1535
Swiss Prot:P13498
Source:KLH conjugated synthetic peptide derived from human CK18 Cytochrome b245 Light Chain/p22phox:21-120/195
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Mox1 and the glycoprotein gp91-phox are largely related proteins that are essential components of the NADPH oxidase. The superoxide-generating NADPH oxidase is present in phagocytes, neuroepithelial bodies, vascular smooth muscle cells and endothelial cells. It includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane, where they associate with the flavocytochrome cytochrome b558 to form the active enzyme complex. The p22- and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Cytochrome b245 Ligh;CYBA;Cytochrome b 245 alp;ytochrome b 245 ligh;ytochrome b alpha po; p22-PHOX;p22phox;CY24A_HUMAN;
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