Rabbit Anti-TRP12/TRPV4 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:TRP12/TRPV4
IR:Immunogen Range:301-400/871
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:59341
Swiss Prot:Q9HBA0
Source:KLH conjugated synthetic peptide derived from human TRPV4:301-400/871
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The detection of noxious stimuli (chemical, mechanical, or thermal) occurs predominantly at the peripheral terminals of primary afferent neurons. This information is ultimately transmitted to the central nervous system to evoke appropriate protective reflexes. TRPV4 is a non selective calcium permeant, swell activated, cation channel probably involved in osmotic and mechano sensitivity. Activation by exposure to hypotonicity within the physiological range, low pH, citrate and phorbol esters exhibits an outward rectification. Once activated the channel seems to be regulated in a calmodulin dependent manner, with a negative feedback mechanism.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
Flow-Cyt(1ug/test)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： TRP12/TRPV4;osm-9-like TRP chann;TRPC 4;OTRPC4;Vanilloid receptor-l;TRP12;VR4;VROAC;
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