Rabbit Anti-SRXN1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:SRXN1
IR:Immunogen Range:45-137/137
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:140809
Swiss Prot:Q9BYN0
Source:KLH conjugated synthetic peptide derived from human SRXN1:45-137/137
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Sulfiredoxin, also designated Sulfiredoxin-1 and chromosome 20 open reading frame 139 (C20orf139), is a cytoplasmic antioxidant protein involved in signaling through catalytic reduction of oxidative modifications. It regulates peroxiredoxins (PRXs), a family of proteins that reduce hydroperoxides, by reducing the conserved cysteine from sulfinic to sulfenic acid. This impacts the role of PRX in the reduction of other downstream transcription factors and kinase signaling pathways. The Sulfiredoxin protein specifically acts on the PRDX1, PRDX2, PRDX3 and PRDX4 peroxiredoxins, but not on PRDX5 or PRDX6. Sulfiredoxin acts as a phosphotransferase and an athioltransferase and is widely expressed, with highest levels detected in lung, spleen, kidney and thymus tissues.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： SRXN1;C20orf1392;Chromosome 20 open r;dJ850E9.2;Npn3;SRX1;Npn31;SRXN1_HUMAN;
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