Rabbit Anti-BBC3/PUMA Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:BBC3/PUMA
IR:Immunogen Range:131-180/193
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:27113
Swiss Prot:Q96PG8
Source:KLH conjugated synthetic peptide derived from human BBC3:131-180/193
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
本品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： BBC3/PUMA;PUMA; bcl-2 binding compo;BBC3;BCL 2 binding compon;BCL2 binding compone;JFY1;BBC3_RAT;
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