Rabbit Anti-TRIM21 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:TRIM21
IR:Immunogen Range:301-400/475
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6737
Swiss Prot:P19474
Source:KLH conjugated synthetic peptide derived from human TRIM21 N-terminus:301-400/475
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： TRIM21;52 kDa ribonucleopro;52 kDa Ro protein;52kD Ro/SSA autoanti;Autoantigen Ro/SSA;RNF81;Ro52;RO52_HUMAN;
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