Rabbit Anti-Neurokin B receptor Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Neurokin B receptor
IR:Immunogen Range:151-250/440
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6870
Swiss Prot:P29371
Source:KLH conjugated synthetic peptide derived from human NKR:151-250/440
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.
Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg/Test )
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Guinea Pig
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： MGC148060;MGC148061;Neurokinin B recepto;Neurokinin beta rece; NK 3 receptor;NK 3R;NK-3 receptor;NK3R_HUMAN;
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