Rabbit Anti-ROCK1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ROCK1
IR:Immunogen Range:1001-1200/1354
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6093
Swiss Prot:Q13464
Source:KLH conjugated synthetic peptide derived from human ROCK1:1001-1200/1354
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Rabbit
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： ROCK1;p160 ROCK1;p160ROCK;Renal carcinoma anti;Rho associated coile; Rho associated prot;Rho-associated coile;ROCK1_HUMAN;
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