Product Name:Saralasin
CAS No.:34273-10-4
Synonyms:(Sar1,Val5,Ala8)-Angiotensin II;肌丙抗增壓素
Catalog No.:108P22
Brand:HongTide(上海鴻肽生物)
Description:Saralasin是血管緊張素II的改造片段多肽,序列中的個(gè)氨基酸Asp換成了Sar,第5位的氨基酸由Ile換成Val,第8個(gè)氨基酸Phe換成了Ala,由8個(gè)氨基酸組成的多肽,序列中含有非天然氨基酸Sar,可以用于高血壓的鑒別診斷藥。Saralasin對(duì)血漿血管緊張肽Ⅱ水平過(guò)高所致高血壓患者有顯著降血壓作用。
Saralasin is a modified fragment peptide of angiotensin II, with the first amino acid Asp replaced by Sar, the fifth amino acid Ile replaced by Val, and the eighth amino acid Phe replaced by Ala. It is a peptide composed of eight amino acids and contains a non natural amino acid Sar in the sequence, which can be used as a differential diagnostic drug for hypertension. Saralasin has a significant antihypertensive effect on patients with hypertension caused by high plasma angiotensin II levels.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Sar-RVYVHPA |
Sequence(3-letter code) | H-Sar-Arg-Val-Tyr-Val-His-Pro-Ala-OH |
Peptide Structure |
|
Molecular Formula | C42H65N13O10 |
Molecular Weight | 912.06 |
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關(guān)鍵字: Saralasin;34273-10-4;肌丙抗增壓素;(Sar1,Val5,Ala8)-Ang;多肽;
上海鴻肽生物科技有限公司(簡(jiǎn)稱(chēng):鴻肽生物)是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷(xiāo)售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來(lái),秉持“用質(zhì)量作船, 以服務(wù)為帆,為科研服務(wù)”的企業(yè)理念,為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。