R-2,3-二羥基異戊酸是支鏈氨基酸合成途徑的一個(gè)中間代謝產(chǎn)物,是合成纈氨酸和異亮氨基酸代謝途徑的中間代謝產(chǎn)物,本產(chǎn)品為生物過(guò)程生產(chǎn),具有良好的手型。HMDB ID HMDB0012141
(R) 2,3-Dihydroxy-isovalerate is an intermediate in valine, leucine and isoleucine biosynthesis. The pathway of valine biosynthesis is a four-step pathway that shares all of its steps with the parallel pathway of isoleucine biosynthesis. These entwined pathways are part of the superpathway of leucine, valine, and isoleucine biosynthesis , that generates not only isoleucine and valine, but also leucine. (R) 2,3-Dihydroxy-isovalerate is generated from 3-Hydroxy-3-methyl-2-oxobutanoic acid via the enzyme ketol-acid reductoisomerase (EC 1.1.1.86) then it is converted to 2-Oxoisovalerate via the dihydroxy-acid dehydratase (EC:4.2.1.9).
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