Product Name:Neuropeptide Y Antagonist
CAS No.:158859-98-4
Synonyms:受體拮抗劑多肽GR 231118
Catalog No.:218P312
Brand:HongTide(上海鴻肽生物)
Description:Neuropeptide Y Antagonist是一種有效的神經(jīng)肽 Y (NPY) Y1 受體拮抗劑多肽(rY1 和 hY1 受體的 pA2 = 10 和 10.5),序列中是一個(gè)二聚體多肽,通過酰胺鍵形成的二聚體多肽。Neuropeptide Y Antagonist也是一種有效和選擇性的 NPY Y4 受體激動(dòng)劑(rY2、hY4 和 rY5 受體的 pEC50 值分別為 6.0、8.6 和 6.1),由同一段序列通過酰胺鍵形成的二聚體多肽。在體內(nèi)抑制大鼠的食物攝入,Neuropeptide Y Antagonist在體外也對(duì)神經(jīng)肽 FF (NPFF) 受體具有親和力 (Ki = 43-73 nM)。
Neuropeptide Y Antagonist is an effective Neuropeptide Y (NPY) Y1 receptor antagonist peptide (pA2 of rY1 and hY1 receptors=10 and 10.5). The sequence is a dimer peptide formed by amide bond. Neuropeptide Y Antigonist is also an effective and selective NPY Y4 receptor agonist (pEC50 values of 6.0, 8.6, and 6.1 for rY2, hY4, and rY5 receptors, respectively), a dimeric peptide formed from the same sequence through amide bonds. Neuropeptide Y Antagonist also has affinity for Neuropeptide FF (NPFF) receptor in vitro (Ki=43-73 nM) by inhibiting food intake of rats in vivo.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | IEP-Dapa-YRLRY-NH2; IEP-Dapa-YRLRY-NH2;Amide Bridge=2-4*, 4-2* |
Sequence(3-letter code) | H-Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH2; H-Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH2;Amide Bridge=Glu2-Dap4*,Dap4-Glu2* |
Peptide Structure |
|
Molecular Formula | C110H170N34O24 |
Molecular Weight | 2352.77 |
訂購聯(lián)系方式:
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關(guān)鍵字: 158859-98-4;Neuropeptide Y Antag;受體拮抗劑多肽GR 231118;多肽;多肽合成;
上海鴻肽生物科技有限公司(簡(jiǎn)稱:鴻肽生物)是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來,秉持“用質(zhì)量作船, 以服務(wù)為帆,為科研服務(wù)”的企業(yè)理念,為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。