Product Name：[Pyr3]-Amyloid β-Protein (3-42)
CAS No.：183449-57-2
Synonyms：淀粉樣蛋白[Pyr3]-Amyloid β-Protein (3-42)
Catalog No.：107P96
Brand：HongTide（上海鴻肽生物）
Description：[Pyr3]-Amyloid β-Protein (3-42)是β淀粉樣肽的改造序列，選取序列中第3-42個氨基酸，序列中第1個氨基酸由Glu換成Pyr。發(fā)現(xiàn) (Pyr3)-淀粉樣蛋白 β-蛋白 (3-42) 是沉積在阿爾茨海默病和唐氏綜合癥患者大腦中的主要淀粉樣蛋白 β-肽結構。 因此，建議 (Pyr3)-Aβ (3-42) 在大腦中積累并觸發(fā)不溶性淀粉樣蛋白 β-肽沉積物的形成。 [Pyr3]-Amyloid β-Protein (3-42)可用于研究截短的 Aβ 序列的朊病毒樣行為和 tau 依賴性細胞毒性。
[Pyr3] - Amyloid β- Protein (3-42) is β The modified sequence of amyloid peptide was selected, with the 3rd to 42nd amino acids in the sequence, and the first amino acid in the sequence was replaced by Pyr instead of Glu. Discovery (Pyr 3)- Amyloid protein β- Protein (3-42) is the main amyloid protein deposited in the brain of patients with Alzheimer's disease and Down syndrome β- Peptide structure. Therefore, it is recommended that (Pyr 3)- A β (3-42) Accumulation and triggering of insoluble amyloid protein in the brain β- The formation of peptide deposits. [Pyr3] - Amyloid β- Protein (3-42) can be used to study truncated A β Prion like behavior and tau dependent cytotoxicity of sequences.
Purity (HPLC) ≥75.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Pyr-FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
Sequence(3-letter code) | Pyr-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH |
Peptide Structure | ![[Pyr3]-Amyloid β-Protein (3-42) 183449-57-2.png](/SupplyImg/2023-06-09/6382190476393841092167364.jpg "[Pyr3]-Amyloid β-Protein (3-42) 183449-57-2.png")
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Molecular Formula | C196H299N53O55S |
Molecular Weight | 4309.97 |
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關鍵字： [Pyr3]-Amyloid β-Pro;183449-57-2;淀粉樣蛋白;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術轉讓為主要業(yè) 務科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質量作船， 以服務為帆，為科研服務”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質的服務及產(chǎn)品。