Product Name：Cotadutide acetate
CAS No.：1686108-82-6
Synonyms：雙重肽激動劑多肽Cotadutide
Catalog No.：218P269
Brand：HongTide（上海鴻肽生物）
Description：Cotadutide acetate是胰高血糖素樣肽-1 (GLP-1)和胰高血糖素受體 (glucagon receptor) 的有效雙重肽激動劑多肽，序列中含有31個(gè)氨基酸，多肽的N端由棕櫚酸封閉，多肽結(jié)構(gòu)中含有一個(gè)酰胺鍵組成的環(huán)狀結(jié)構(gòu)，EC50 值分別為 6.9 pM 和 10.2 pM。Cotadutide acetate有促進(jìn)減肥和控制血糖的能力，有潛力用于肥胖癥和 2 型糖尿病 (T2D) 的研究。
Cotadutide acetate is an effective dual peptide agonist peptide of glucagon like peptide-1 (GLP-1) and glucagon receptor. The sequence contains 31 amino acids. The N-terminal of the polypeptide is blocked by palmitic acid. The peptide structure contains a ring structure composed of an amide bond. The EC50 values are 6.9 pM and 10.2 pM, respectively. Cotadutide acetate has the ability to promote weight loss and control blood sugar, and has the potential to be used in the study of obesity and type 2 diabetes (T2D).
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Pal-EHSQGTFTSDKSEYLDSERARDFVAWLEAGG (Amide bridge: Glu1-Lys10) |
Sequence(3-letter code) | Pal-Glu-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Lys-Ser-Glu-Tyr-Leu-Asp-Ser-Glu-Arg-Ala-Arg-Asp-Phe-Val-Ala-Trp-Leu-Glu-Ala-Gly-Gly-OH(Amide bridge: Glu1-Lys10) |
Peptide Structure |  |
Molecular Formula | C169H256N42O57 |
Molecular Weight | 3788.14 |
訂購聯(lián)系方式：
上海鴻肽生物科技有限公司
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郵箱：sales1@hongtide.com
關(guān)鍵字： 1686108-82-6;Cotadutide acetate;雙重肽激動劑多肽;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。