Three subclasses of IgG can be isolated from the serum of camelids. Conventional IgG1 contains molecules of ~170KD, which upon reduction yield 50KD heavy chains and large 30KD light chains. IgG2 and IgG3 are distinct in that they do not incorporate light chains. The IgG2 contain molecules of ~100KD, which upon reduction yield only heavy chains of ~49KD. The IgG3 contain molecules of ~90KD, which upon reduction yield only heavy chains of ~46KD.
Alpaca Total IgG (TKPA101) is an isotype control antibody, which can be used as negative controls to help differentiate non-specific background signal from specific antibody signal.
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