Product Name:Margatoxin
CAS No.:145808-47-5
Synonyms:Margatoxin (9CI);斑蝎毒素
Catalog No.:211P16
Brand:HongTide(上海鴻肽生物)
Description:Margatoxin 是一種有效的 KV1.3 通道阻滯劑多肽,序列中含有39個(gè)氨基酸,并且包含3對(duì)二硫鍵,IC50為36 pM,但對(duì)鈣激活通道沒(méi)有影響。Margatoxin可以減少VEGF誘導(dǎo)的跨膜鈣流入和人內(nèi)皮細(xì)胞中一氧化氮的產(chǎn)生。
Margatoxin is an effective KV1.3 channel blocker peptide with a sequence of 39 amino acids and 3 pairs of disulfide bonds. Its IC50 is 36 pM, but it has no effect on calcium activated channels. Margatoxin can reduce VEGF induced transmembrane calcium influx and nitric oxide production in human endothelial cells.
Purity (HPLC) ≥75.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) |
TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH(Disulfide bridge:Cys7-Cys29;Cys13-Cys34;Cys17-Cys39) |
Sequence(3-letter code) |
H-Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His-OH(Disulfide bridge:Cys7-Cys29;Cys13-Cys34;Cys17-Cys39) |
Peptide Structure |
|
Molecular Formula | C178H286N52O50S7 |
Molecular Weight | 4178.94 |
訂購(gòu)聯(lián)系方式:
上海鴻肽生物科技有限公司
手機(jī): +86-18018095145 (同微信號(hào))
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郵箱:sales1@hongtide.com
關(guān)鍵字: Margatoxin;145808-47-5;Margatoxin (9CI);斑蝎毒素;多肽;
上海鴻肽生物科技有限公司(簡(jiǎn)稱:鴻肽生物)是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來(lái),秉持“用質(zhì)量作船, 以服務(wù)為帆,為科研服務(wù)”的企業(yè)理念,為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。