Host:Mouse

Target Protein:PTPN2

IR:Immunogen Range:

Clonality:Monoclonal

Isotype:IgG1/Kappa

Entrez Gene:5771

Swiss Prot:P17706

Source:: 

Purification:Affinity purified by Protein G

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.  Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]

Size:50ul

Concentration:1mg/ml

Applications:WB(1:1000-1:5000)
IHC-P(1:50-1:100)
ICC(1:50)

Cross Reactive Species:Human
Mouse
Rat