Host:Rabbit
Target Protein:SIRT3
IR:Immunogen Range:300-399/399
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:23410
Swiss Prot:Q9NTG7
Source:KLH conjugated synthetic peptide derived from human SIRT3:300-399/399
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Background:SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IHC-P(1:20-50)
IHC-F(1:20-50)
ICC(1:100)
Cross Reactive Species:Human
Mouse
Rat