Product Name:Laminin (925-933)
CAS No.:110590-60-8
Synonyms:層粘連蛋白(925-933)
Catalog No.:168P02
Brand:HongTide(上海鴻肽生物)
Description:Laminin (925-933) acetate是由9個(gè)氨基酸組成的直鏈多肽,源自與層粘連蛋白受體結(jié)合的層粘連蛋白 B1 鏈的殘基 925-933。層粘連蛋白是細(xì)胞外基質(zhì)糖蛋白家族,是基底膜的主要非膠原成分。它們與多種生物過(guò)程有關(guān),包括細(xì)胞粘附、分化、遷移、信號(hào)傳導(dǎo)、神經(jīng)突生長(zhǎng)和轉(zhuǎn)移。層粘連蛋白由 3 條不同的鏈組成:層粘連蛋白 α、β 和 γ(以前分別為 A、B1 和 B2)。層粘連蛋白 β 1 鏈具有 7 個(gè)結(jié)構(gòu)不同的結(jié)構(gòu)域,它與其他 β 鏈異構(gòu)體共享這些結(jié)構(gòu)域。層粘連蛋白,β1 在大多數(shù)產(chǎn)生基底膜的組織中表達(dá),并且是構(gòu)成層粘連蛋白 1 的 3 條鏈之一,層粘連蛋白 1 是從 Engelbreth-Holm-Swarm (EHS) 腫瘤中分離的個(gè)層粘連蛋白。 β1 鏈中涉及細(xì)胞附著、趨化性和與層粘連蛋白受體結(jié)合的序列被鑒定并顯示具有抑制轉(zhuǎn)移的能力。
Laminin (925-933) acetate is a straight chain peptide composed of 9 amino acids, derived from the residue 925-933 of the laminin B1 chain that binds to the laminin receptor. Laminin is a family of extracellular matrix glycoproteins that are the main non collagen component of the basement membrane. They are involved in a variety of biological processes, including cell adhesion, differentiation, migration, signal transduction, neurite growth and metastasis. Laminin is composed of three different chains: laminin α、β And γ (Previously A, B1, and B2, respectively). Laminin β 1 chain has 7 structural domains with different structures, which are different from others β Chain isomers share these structural domains. Laminin, β 1 is expressed in most tissues that produce basement membranes and is one of the three chains that make up laminin 1, which is the first laminin isolated from Engelbreth Holm Swarm (EHS) tumors. β The sequences involved in cell adhesion, chemotaxis, and binding to laminin receptors in the 1 strand have been identified and shown to have the ability to inhibit metastasis.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | CDPGYIGSR |
Sequence(3-letter code) | H-Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-OH |
Peptide Structure |
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Molecular Formula | C40H62N12O14S1 |
Molecular Weight | 967.06 |
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關(guān)鍵字: Laminin (925-933);110590-60-8;層粘連蛋白(925-933);多肽;多肽合成;
上海鴻肽生物科技有限公司(簡(jiǎn)稱:鴻肽生物)是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來(lái),秉持“用質(zhì)量作船, 以服務(wù)為帆,為科研服務(wù)”的企業(yè)理念,為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。