Host:Rabbit

Target Protein:HDAC8

IR:Immunogen Range:

Clonality:Monoclonal

Isotype:IgG

Entrez Gene:55869

Swiss Prot:Q9BY41

Source:Recombinant human HDAC8 protein (1-150aa): 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
IHC-P(1:50-200)
IHC-F(1:400-800)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat

本產(chǎn)品僅供科研使用。不能用于人和動物治療等其它臨床診斷使用！