Host:Rabbit

Target Protein:Phospho-FAK (Tyr576 + Tyr577)

IR:Immunogen Range:ST(p-Y)(p-Y)KA

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:5747

Swiss Prot:Q05397

Source:KLH conjugated Synthesised phosphopeptide derived from human FAK around the phosphorylation site of Tyr576/577:ST(p-Y)(p-Y)KA 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/Test)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
Rabbit

本產(chǎn)品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷使用！