Product Name：C3bot (154-182)
CAS No.：1246280-79-4
Synonyms：梭菌C3蛋白(154-182)
Catalog No.：218P166
Brand：HongTide（上海鴻肽生物）
Description：C3bot (154-182)是梭菌C3蛋白的轉(zhuǎn)移酶缺陷型神經(jīng)營(yíng)養(yǎng)多肽片段，是由29個(gè)氨基酸組成的直鏈多肽。C3bot (154-182)在亞微摩爾濃度下促進(jìn)海馬神經(jīng)元的軸突和樹(shù)突生長(zhǎng)和分支，還促進(jìn)器官型海馬/內(nèi)嗅切片培養(yǎng)物中靶組織的神經(jīng)再生，可以通過(guò)非酶機(jī)制降低活性神經(jīng)元 RhoA 的水平，具備增強(qiáng)脊髓損傷小鼠模型的功能恢復(fù)和再生的生活學(xué)功能。
C3bot (154-182) is a transferase-deficient neurotrophic peptide fragment of Clostridium C3 protein, which is a straight chain peptide composed of 29 amino acids. C3bot (154-182) promotes the growth and branching of axons and dendrites in hippocampal neurons at submicromolar concentrations, and also promotes nerve regeneration of target tissues in organotypic hippocampal/olfactory slice cultures. It can reduce the level of reactive neuron RhoA through non enzymatic mechanisms, and has the biological function of enhancing functional recovery and regeneration in spinal cord injury mouse models.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | VAKGSKAGYIDPISAFAGQLEMLLPRHST |
Sequence(3-letter code) | H-Val-Ala-Lys-Gly-Ser-Lys-Ala-Gly-Tyr-Ile-Asp-Pro-Ile-Ser-Ala-Phe-Ala-Gly-Gln-Leu-Glu-Met-Leu-Leu-Pro-Arg-His-Ser-Thr-OH |
Peptide Structure | 
|
Molecular Formula | C137H221N37O40S1 |
Molecular Weight | 3058.55 |
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關(guān)鍵字： 1246280-79-4;C3bot (154-182);梭菌C3蛋白(154-182);多肽;多肽合成;
上海鴻肽生物科技有限公司（簡(jiǎn)稱(chēng)：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷(xiāo)售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來(lái)，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。