Host:Rabbit
Target Protein:ATP7B
IR:Immunogen Range:1351-1465/1465
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:540
Swiss Prot:P35670
Source:KLH conjugated synthetic peptide derived from human ATP7B:1351-1465/1465
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Pig
.
本產(chǎn)品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷使用!
關(guān)鍵字: PWD; Toxic milk;tx;WND;ATP7B;
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