Product Name：Spadin
CAS No.：1270083-24-3
Synonyms：抑制劑多肽Spadin
Catalog No.：218P148
Brand：HongTide（上海鴻肽生物）
Description：Spadin是一個(gè)強(qiáng)效的抑制劑多肽，這是一個(gè)分泌的多肽，Spadin來自由成熟的NTSR3/Sortilin生成的前導(dǎo)肽，序列中含有18個(gè)氨基酸。研究表明spadin在小鼠上顯示出對(duì)抑郁的抵抗力，在實(shí)驗(yàn)中連續(xù)給小鼠用藥四天，不但表現(xiàn)出很強(qiáng)的抗抑郁效果，并且也助長了海馬CREB蛋白的磷酸化和神經(jīng)系統(tǒng)發(fā)育。
Spadin is a potent inhibitor peptide, which is a secreted peptide. Spadin is a precursor peptide generated by freely maturing NTSR3/Sortilin, with a sequence containing 18 amino acids. Research has shown that spadin exhibits resistance to depression in mice. In the experiment, continuous administration of spadin to mice for four days not only showed strong antidepressant effects, but also promoted the phosphorylation of hippocampal CREB protein and nervous system development.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | YAPLPRWSGPIGVSWGLR |
Sequence(3-letter code) | H-Tyr-Ala-Pro-Leu-Pro-Arg-Trp-Ser-Gly-Pro-Ile-Gly-Val-Ser-Trp-Gly-Leu-Arg-OH |
Peptide Structure | 
|
Molecular Formula | C96H142N26O22 |
Molecular Weight | 2012.35 |
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關(guān)鍵字： 1270083-24-3;Spadin;抑制劑多肽Spadin;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。