Product Name：Neurotensin
CAS No.：39379-15-2；55508-42-4
Synonyms：Neurotensin(1-13)；神經(jīng)降壓肽1-13
Catalog No.：183P02
Brand：HongTide（上海鴻肽生物）
Description：Neurotensin屬于一種神經(jīng)降壓肽，在生物體內(nèi)主要作用于各種結(jié)腸直腸癌和胰腺癌，同時對神經(jīng)降壓素受體 (neurotensin receptor) 具有高親和力，具有很強(qiáng)的特異性，主要對血管以及降血壓起到作用。Neurotensin是由13個氨基酸組成的多肽，多肽合成中Neurotensin序列中兩個連續(xù)的Arg，需要選擇合理的縮合劑。另外，序列中的-Glu-Asn-片段也容易發(fā)生水解等副反應(yīng)，所以在合成多肽過程中，面對一些條件劇烈的反應(yīng)，比如脫除Fmoc，需要加入一些防止副反應(yīng)發(fā)生的添加劑。
Neurotensin is a kind of neurotensin, which mainly acts on various colorectal cancer and pancreatic cancer in vivo, and has high affinity and strong specificity for neurotensin receptor, which mainly plays a role in blood vessels and lowering blood pressure. Neurotensin is a peptide composed of 13 amino acids. In peptide synthesis, two consecutive Args in the Neurotensin sequence require the selection of a reasonable condensation agent. In addition, the - Glu Asn fragment in the sequence is also prone to side reactions such as hydrolysis. Therefore, in the process of synthesizing peptides, when facing some severe reactions, such as the removal of Fmoc, it is necessary to add some additives to prevent side reactions from occurring.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Pyr-LYENKPRRPYIL |
Sequence(3-letter code) | Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH |
Peptide Structure | 
|
Molecular Formula | C78H121N21O20 |
Molecular Weight | 1672.92 |
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上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。