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Description
Motavizumab (MEDI-524, NUMAX, NISTmAb) is a second generation monoclonal antibody (mAb) derived from palivizumab (Synagis) using affinity maturation techniques. Motavizumab is currently undergoing US Food and Drug Administration review as a treatment for respiratory syncytial virus (RSV) prophylaxis. It has been evaluated in large-scale clinical studies, and has demonstrated efficacy in reducing the disease burden of RSV in high-risk infant populations.Motavizumab (MEDI-524, NUMAX, NISTmAb) has higher affinity and a longer half-life, was effective in reducing RSV hospitalization in high-risk full-term infants in the US, but was not licensed due to safety concerns (allergic reactions) .
Catalog No.
DVV02803
Host species
Humanized
Species reactivity
HRSV-A
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Concentration
3.06 mg/ml
Purity
>95% by SDS-PAGE.
Clonality
Monoclonal
Isotype
IgG1, kappa
Applications
Research Grade Biosimilar
Target
F, Fusion glycoprotein F0
Purification
Protein A or G purified from cell culture supernatant.
Endotoxin level
Please contact with the lab for this information.
Expression system
XtenCHO
Accession
P03420
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
Alternative Names
MEDI-524,NUMAX, NISTmAb, CR9503, CAS: 677010-34-3, Human Respiratory Syncytial Virus (HRSV)
Note
For research use only. Not suitable for clinical or therapeutic use.
關(guān)鍵字： Motavizumab;莫維組單抗;677010-34-3;F;
武漢佰樂博生物（Biolab Reagents）由五位畢業(yè)于華中科技大學(xué)，華中農(nóng)業(yè)大學(xué)，武漢大學(xué)等知名高校，且具有二十年工作經(jīng)驗(yàn)的生命科學(xué)領(lǐng)域頂級研究者創(chuàng)立于2021年，憑借豐富的產(chǎn)品開發(fā)經(jīng)驗(yàn)，利用全球領(lǐng)先的技術(shù)平臺，引進(jìn)和整合全球高品質(zhì)的蛋白、抗體和試劑盒產(chǎn)品。目前，佰樂博生物作為法國AntibodySystem和ProteoGenix在亞洲的獨(dú)家總代理，提供近30,000種生命科學(xué)試劑，核心產(chǎn)品涵蓋蛋白、抗體和試劑盒，旨在為科研工作者提供專業(yè)、全面、可靠的試劑支持，推動生命科學(xué)研究的深入發(fā)展。