Anti-BubR1
有絲分裂檢驗(yàn)點(diǎn)蛋白BubR1抗體
Host: Rabbit
Target Protein: Anti-BubR1
Concentration: 1mg/ml
Predicted MW: 120
IR:Immunogen
Range:
751-850/1050
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 701
Swiss Prot: O60566
Source: KLH conjugated synthetic peptide derived from human BubR1-751-850/1050
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background: This gene encodes a kinase involved in spindle checkpoint function. The protein
has been localized to the kinetochore and plays a role in the inhibition of the
anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase
and ensuring proper chromosome segregation. Impaired spindle checkpoint
function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
BubR1是存在于哺乳動(dòng)物中的有絲分裂檢查點(diǎn)基因家族Mad3的同源基因,其編碼蛋白BubR1是一個(gè)多結(jié)構(gòu)域蛋白,在監(jiān)測細(xì)胞有絲分裂前中期向后期轉(zhuǎn)化的過程中扮演重要的角色。
本產(chǎn)品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷使用！
關(guān)鍵字： BubR1;有絲分裂檢驗(yàn)點(diǎn)蛋白BubR1抗體;SSK 1;BUB1B;MAD3/BUB1-related pr;
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