Product Name：Pasireotide
CAS No.：396091-73-9；396091-76-2
Synonyms：SOM230；帕西瑞肽
Catalog No.：218P051
Brand：HongTide（上海鴻肽）
Description：帕西瑞肽是一種結(jié)構(gòu)為環(huán)六肽的生長抑素類似物，序列中含有4個非天然氨基酸，作為藥物主要成分的帕西瑞肽適用于未進(jìn)行垂體手術(shù)或手術(shù)未治愈的庫欣氏病成年患者的治療。同奧曲肽相比，帕西瑞肽有更長的半衰期、能與更多受體結(jié)合，抑制胰腺分泌，抑制腸道蛋白水解酶的活性，通過這些機(jī)制來降低胰腺術(shù)后并發(fā)癥。
Pasireotide is a somatostatin analogue with a cyclic hexapeptide structure and contains four unnatural amino acids in its sequence. As a main component of the drug, Pasireotide is suitable for the treatment of adult patients with Cushing's disease who have not undergone pituitary surgery or have not been cured by surgery. Compared with octreotide, Pasireotide has a longer half life, can bind to more receptors, inhibit pancreatic secretion, and inhibit the activity of intestinal proteolytic enzymes. These mechanisms can reduce postoperative complications of pancreatic surgery.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | cyclo[Y(Bzl)F-Hyp(Bom)-Phg-d-W-K] |
Sequence(3-letter code) | cyclo[Tyr(Bzl)-Phe-Hyp(Bom)-Phg-D-Trp-Lys] |
Peptide Structure | 
|
Molecular Formula | C58H66N10O9 |
Molecular Weight | 1047.21 |
訂購聯(lián)系方式：
上海鴻肽生物科技有限公司
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郵箱：sales1@hongtide.com
關(guān)鍵字： 396091-73-9;396091-76-2;Pasireotide;帕西瑞肽;多肽;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。