產(chǎn)品屬性：

Cas No.1638504-66-1

別名 N/A

化學(xué)名 N/A

分子式 C24H20F2N4O5S

分子量 514.5

溶解度 Soluble in DMSO

儲(chǔ)存條件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM. IC50: 3.7 nM (INST)[1]

HIV-1 integrase inhibitor 4 (compound 4f) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM. HIV-1 integrase inhibitor 4 shows potent activity against recombinant HIV IN in biochemical assays and good efficacy in assays done in cell culture against a broad panel of viral mutants carrying the major RAL and DTG IN resistance mutations[1].

[1]. Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15;11(4):1074-81.