產(chǎn)品屬性:
產(chǎn)品名稱
規(guī)格
CAS號
型號
H1 Inhibitor 2
250mg 500mg
2244895-42-7
EY-Y0164524
Cas No.2244895-42-7
別名 N/A
化學名 N/A
分子式 C26H22N4O
分子量 406.48
溶解度 Soluble in DMSO
儲存條件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: IDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM[1]. IC50: 110 nM (IDH1)[1].
[1]. Jakob CG, et al. Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. J Med Chem. 2018 Aug 9;61(15):6647-6657.
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