產(chǎn)品屬性:
產(chǎn)品名稱
規(guī)格
CAS號
型號
CM10
10mg 5mg 50mg 100mg 500mg
692269-09-3
EY-Y0164085
Cas No.692269-09-3
別名 N/A
化學(xué)名 N/A
分子式 C20H23N3O
分子量 321.42
溶解度 DMSO: 125 mg/mL (388.90 mM)
儲存條件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: CM10 is a potent and selective aldehyde dehydrogenase 1A family inhibitor (ALDH1Ai), with IC50s of 1700, 740, and 640 nM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. CM10 does not inhibit any of the other ALDH family members. CM10 can regulate metabolism and has anti-cancer activity[1].
[1]. Chefetz I, et al. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Rep. 2019 Mar 12;26(11):3061-3075.e6.
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