產(chǎn)品屬性：

Cas No.618913-30-7

別名 N/A

化學名 N/A

分子式 C10H12N4O2S

分子量 252.29

溶解度 DMSO : 125 mg/mL (495.46 mM)

儲存條件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat.

AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat. It is 10 to 19-fold selective compare to the closely related lactoperoxidase and thyroid peroxidase; >70-fold to a broad panel of other enzymes, ion channels, and receptors. In isolated human neutrophils, 1 μM AZD5904 inhibits PMA stimulated HOCl by >90%[1].

[1]. Myeloperoxidase (MPO) inhibitor.