產(chǎn)品屬性:
產(chǎn)品名稱 | 規(guī)格 | CAS號 | 型號 |
7-hydroxy Chlorpromazine (hydrochloride) | 2.5mg | 51938-11-5 | EY-Y0163673 |
Cas No.51938-11-5
別名 N/A
化學名 N/A
分子式 C17H19ClN2OS?HCl
分子量 371.3
溶解度 Methanol: slightly soluble
儲存條件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
7-hydroxy Chlorpromazine is an active metabolite of the typical antipsychotic chlorpromazine .1 In vivo, 7-hydroxy chlorpromazine (5 mg/kg) increases plasma prolactin levels in male rats. It also reverses D-amphetamine-induced depression of the dopaminergic neuronal firing rate in the rat substantia nigra in rats when administered at a dose of 1.6 mg/kg.2
1.Meltzer, H.Y., Fang, V.S., Simonovich, M., et al.Effect of metabolites of chlorpromazine on plasma prolactin levels in male ratsEur. J. Pharmacol.41(4)431-436(1977) 2.Bunney, B.S., and Aghajanian, G.K.A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neuronsLife Sci.15(2)309-318(1974)
關(guān)鍵字: 51938-11-5;C17H19ClN2OS?HCl;7-hydroxy Chlorproma;
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