產(chǎn)品屬性:
產(chǎn)品名稱
規(guī)格
CAS號
型號
6-O-desmethyl Donepezil
500μg 1mg 5mg
120013-56-1
EY-Y0163664
Cas No.120013-56-1
別名 N/A
化學(xué)名 N/A
分子式 C23H27NO3
分子量 365.5
溶解度 Chloroform: soluble,Methanol: soluble
儲(chǔ)存條件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: 6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil . It is formed through dealkylation by the cytochrome P450 (CYP) isoform CYP2D6. It inhibits human ether a go-go (hERG) channels (IC50 = 1.5 μM in HEK293 cells expressing hERG).
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