中文名稱
英文名字
N1-AcSPD; N-[3-[(4-aminobutyl)amino]propyl]-acetamide, dihydrochloride
供應商
開曼生物
產(chǎn)品貨號
9001535-1
背景資料
N1-Acetylspermidine is an acetyl derivative of spermidine (Item No. 14918) that acts as a substrate for polyamine oxidase (PAO).{26260} In peroxisomes, PAO oxidizes N1-acetylspermidine to 3-acetamidopropanal and putrescine, a positively charged polyamine that binds DNA and is involved in various cellular processes including cell division, differentiation, and membrane function.{26259,23742,23743,12989} N1-Acetylspermidine has been used to examine the interaction between DNA and polyamines during the cleavage of phosphodiester bonds at apurinic/apyrimidinic sites in DNA.{27034}
產(chǎn)品描述
A substrate for polyamine oxidase that is oxidized to 3-acetamidopropanal and putrescine, a polyamine involved in the division, differentiation, and membrane function of cells; used to examine the interaction between DNA and polyamines during the cleavage of phosphodiester bonds at apurinic/apyrimidinic sites in DNA
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