Description: AM4113 is a cannabinoid receptor 1 (CB1)-selective antagonist. AM4113 reverts the effects of cannabidiol on cue and stress-induced reinstatement of cocaine-seeking behaviour in mice. AM4113 inhibits heroin self-administration without depressive side effects in rat. AM4113 Retains the Therapeutic Efficacy of the Inverse Agonist Rimonabant for Nicotine Dependence and Weight Loss with Better Psychiatric Tolerability
Name: AM4113
CAS#: 614726-85-1
Chemical Formula: C17H12Cl3N3O
Exact Mass: 379.0046
Molecular Weight: 380.653
Elemental Analysis: C, 53.64; H, 3.18; Cl, 27.94; N, 11.04; O, 4.20
Synonym: AM4113; AM-4113; AM 4113;
IUPAC/Chemical Name: 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
InChi Key: BBUKVPCUOHFAQN-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H12Cl3N3O/c1-9-15(17(21)24)22-23(14-7-6-12(19)8-13(14)20)16(9)10-2-4-11(18)5-3-10/h2-8H,1H3,(H2,21,24)
SMILES Code: O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(Cl)C=C3)=C1C)N
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
關鍵字： 614726-85-1;AM4113;
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