Description: AFP 07 free acid is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor. Prostaglandin I2 is an unstable prostanoid which, through the ‘I prostanoid’ (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds.
Name: AFP-07 free acid
CAS#: 788799-13-3
Chemical Formula: C22H30F2O5
Exact Mass: 412.2061
Molecular Weight: 412.47
Elemental Analysis: C, 64.06; H, 7.33; F, 9.21; O, 19.39
Synonym: AFP-07 free acid; AFP 07 free acid; AFP07 free acid;
IUPAC/Chemical Name: Prosta-5,13-dien-18-yn-1-oic acid, 6,9-epoxy-7,7-difluoro-11,15- dihydroxy-16,20-dimethyl-, (5Z,9R,11R,13E,15S,16S)-
InChi Key: PVHIRYQSPDZLLG-HPUAWPBWSA-N
InChi Code: InChI=1S/C22H30F2O5/c1-3-4-5-8-14(2)16(25)12-11-15-17(26)13-18-21(15)22(23,24)19(29-18)9-6-7-10-20(27)28/h9,11-12,14-18,21,25-26H,3,6-8,10,13H2,1-2H3,(H,27,28)/b12-11+,19-9-/t14-,15-,16+,17+,18+,21+/m0/s1
SMILES Code: O=C(O)CCC/C=C(O1)/C(F)(F)[C@H]2[C@@]1([H])C[C@@H](O)[C@@H]2/C=C/[C@@H](O)[C@@H](C)CC#CCC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
關鍵字： 788799-13-3;AFP-07 free acid;
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