Name: PON-PC
CAS#: 135726-46-4
Chemical Formula: C33H64NO9P
Exact Mass: 649.4319
Molecular Weight: 649.8468
Elemental Analysis: C, 60.99; H, 9.93; N, 2.16; O, 22.16; P, 4.77
Description: PON-PC is an oxidized phospholipid containing a truncated 9-carbon fatty acyl chain terminating in an aldehyde at the sn-2 position. It is a component of oxidized LDL formed by oxidation of palmitoyl oleoyl phosphatidylcholine (POPC) and can also be formed via a reaction with ozone in pulmonary surfactant. PON-PC decreases the production of TNF-α, nitric oxide (NO), and NADP+ in primary mouse alveolar macrophages, as well as reduces the bactericidal activity of RAW 264.7 cells, when used at a concentration of 40 μM. Bronchoalveolar lavage fluid (BALF) levels of PON-PC are elevated in mice exposed to cigarette smoke and in aged mice.
IUPAC/Chemical Name: (R)-2-((9-oxononanoyl)oxy)-3-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
InChi Key: PPTNNIINSOQWCE-WJOKGBTCSA-N
InChi Code: InChI=1S/C33H64NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-18-21-24-32(36)40-29-31(30-42-44(38,39)41-28-26-34(2,3)4)43-33(37)25-22-19-16-17-20-23-27-35/h27,31H,5-26,28-30H2,1-4H3/t31-/m1/s1
SMILES Code: O=C(OC[C@H](COP([O-])(OCC[N+](C)(C)C)=O)OC(CCCCCCCC=O)=O)CCCCCCCCCCCCCCC
Appearance: Solid powder
關(guān)鍵字： 135726-46-4;PON-PC;
北京百奧創(chuàng)新科技有限公司是一家專注于生命科學(xué)的科技企業(yè)，由在國(guó)內(nèi)科研試劑領(lǐng)域有著豐富從業(yè)經(jīng)驗(yàn)的技術(shù)團(tuán)隊(duì)和管理團(tuán)隊(duì)組建而成，專營(yíng)進(jìn)口生物試劑，科學(xué)儀器，實(shí)驗(yàn)消耗品等。公司與諸多國(guó)外品牌簽下代理，RD、Abcam、CST、Genetex、Biolegend、ebioscience、polypure、polyplus、Bethyl、Novus等，能為廣大科研用戶提供數(shù)萬(wàn)種試劑、儀器和實(shí)驗(yàn)消耗品。
公司將不斷把上優(yōu)質(zhì)的產(chǎn)品引入國(guó)內(nèi)市場(chǎng)，滿足客戶的需求，公司也將緊跟生命科學(xué)的發(fā)展，為廣大科研工作者探索生命科學(xué)的奧秘奉獻(xiàn)綿薄之力！