Name: MD001
CAS#: 2254605-76-8
Chemical Formula: C25H18O5
Exact Mass: 398.1154
Molecular Weight: 398.41
Elemental Analysis: C, 75.37; H, 4.55; O, 20.08
Description: MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ. It binds to PPARα and PPARγ but does not bind to PPARβ/δ. It increases transcriptional activity of PPARα and PPARγ and glucose consumption. MD001 decreases levels of glucose, insulin, free fatty acids, triglycerides, LDL, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) in blood and reduces the size and number of hepatic lipid droplets in diabetic db/db mice.
IUPAC/Chemical Name: 5,7-dihydroxy-8-methyl-3-[(2E)-1-oxo-3-phenyl-2-propen-1-yl]-4-phenyl-2H-1-benzopyran-2-one
InChi Key: RTYVORPNMMHKDM-OUKQBFOZSA-N
InChi Code: InChI=1S/C25H18O5/c1-15-19(27)14-20(28)22-21(17-10-6-3-7-11-17)23(25(29)30-24(15)22)18(26)13-12-16-8-4-2-5-9-16/h2-14,27-28H,1H3/b13-12+
SMILES Code: O=C(C1=C(C2=CC=CC=C2)C3=C(C(C)=C(O)C=C3O)OC1=O)/C=C/C4=CC=CC=C4
Appearance: Solid powder
關鍵字: 2254605-76-8;MD001;
北京百奧創(chuàng)新科技有限公司是一家專注于生命科學的科技企業(yè),由在國內科研試劑領域有著豐富從業(yè)經(jīng)驗的技術團隊和管理團隊組建而成,專營進口生物試劑,科學儀器,實驗消耗品等。公司與諸多國外品牌簽下代理,RD、Abcam、CST、Genetex、Biolegend、ebioscience、polypure、polyplus、Bethyl、Novus等,能為廣大科研用戶提供數(shù)萬種試劑、儀器和實驗消耗品。
公司將不斷把上優(yōu)質的產(chǎn)品引入國內市場,滿足客戶的需求,公司也將緊跟生命科學的發(fā)展,為廣大科研工作者探索生命科學的奧秘奉獻綿薄之力!